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Wednesday 10 May 2006
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AFRICA: Concern over HIV/TB coinfection drug

[This report does not necessarily reflect the views of the United Nations]

JOHANNESBURG, 25 April (PLUSNEWS) - Experts are concerned that Isoniazid, an antibiotic commonly used to treat tuberculosis (TB) in HIV-positive people, might also result in multi-drug resistant TB (MDR-TB).

Ted Cohen of the Harvard School of Public Health developed a mathematical model that predicted Isoniazid use would reduce TB prevalence and mortality for several years but also would accelerate the development of MDR-TB.

The World Health Organisation recommends Isoniazid for people living with both HIV and TB to prevent latent TB from becoming active.

Cohen, however, noted in a statement: "We're not saying Isoniazid preventive therapy (IPT) policies are ill-advised, but they must be coupled with an understanding that large-scale IPT programmes should be ready to diagnose and treat individuals with MDR-TB as part of the programmes."



Recent AFRICA Reports
New sexual offences bill fails to protect rape survivors,  9/May/06
Abuja AIDS Summit - promises, promises?,  8/May/06
IRIN PlusNews Weekly Issue 282, 5 May 2006,  7/May/06
AIDS voices least heard - study,  7/May/06
African leaders prepare AIDS battle plan,  4/May/06
· AIDS Media Center
· The Global Fund to fight AIDS, Tuberculosis & Malaria
· International Community of Women Living with HIV/AIDS
· International HIV/AIDS Alliance

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